Company Overview

Commense Health is pioneering a deep understanding of the microbiome early in life and its fundamental role in promoting a lifetime of health. Drawing insights from natural exposures to beneficial microbes, Commense is developing approaches to guide the priming, seeding, and maintaining of the microbiome in infants and children. Co-founded by PureTech Health (“PureTech,” LSE: PRTC) and working with the world’s leading microbiome scientists, physicians, and product developers, Commense is developing a novel category of products to address critical unmet needs in pediatric populations.

Position Summary

The Senior Scientist/Team Lead we are seeking will be a key member of Commense’s expanding leadership team, playing a critical role driving forward Commense’s immunology efforts. The Senior Scientist/Team Lead will spearhead the design and execution of studies to assess the ability of human commensal bacteria to elicit immune responses in in vitro cell-based assays, conventional mice, and germ free mouse models.

Candidate profile:

The ideal candidate must be passionate about translating bench findings to the clinic. The ideal candidate will have a mix of academic life science and biopharma industry experience. The candidate will anchor his/her priorities in line with business strategy, make decisions driven by data, influence and collaborate with all internal teams, and thrive in a startup-like environment.

Key responsibilities:

  • In partnership with strategy leaders of the team, design, plan, execute, and interpret in vitro, ex vivo, and in vivo studies using a variety of approaches and techniques
  • Take observations and associations from human studies and develop assays to evaluate cellular pathways of host-microbe interactions
  • Analysis and presentation of study data, provide scientific interpretations and recommendations in both team and company settings
  • Lead and execute research projects independently, and ensure that projects support current company goals
  • Foster a scientific culture of collaboration, innovation, rigor, and transparency
  • Acknowledged authority within the corporation. Act as a leader of large-scale company initiatives. Viewed by peers as a leader and top contributor and by management as a key business partner. Have credibility with external subject matter experts.
  • Train, supervise, and mentor junior staff, as needed


  • Ph.D. in Immunology, Biology, Biochemistry, or related field, with post-doctoral training and significant contributions to the scientific field
  • At least 5 years working in biotech or pharma; experience running science on industry time required
  • Significant experience designing and working with mouse models of disease, managing a colony and experience in maintaining institutional protocols a plus.
  • Expertise in ex vivo studies including flow cytometry, immunohistochemistry, immunology, and cell-based assays
  • Expertise in cell and molecular biology, extensive experience in mammalian cell culture
  • Experience in in vitro pharmacology and assay development is a plus
  • Successful track record of building and leading teams in a technical lead role. Excellent leadership capabilities with demonstrated skill in building, guiding and motivating effective teams and fostering productive research collaborations
  • Outstanding communication, interpersonal, and partnering skills
  • Excellent cross-disciplinary skills in communicating scientific ideas to non-scientist stakeholders to foster collaboration and deliverable-based team work
  • Experience working in the microbiome, autoimmunity, pediatric immunology, host-microbe, or inflammation fields highly desirable
  • Startup experience is highly valued. Ability to adjust rapidly to changing scientific priorities and technologies

Location: Cambridge MA, USA.

Travel: This position requires travel up to 5% domestically and internationally