SENIOR Scientist/Team LEAD - IMMUNOLOGy, In vivo Biology, pharmacology
Commense Health is pioneering a deep understanding of the microbiome early in life and its fundamental role in promoting a lifetime of health. Drawing insights from natural exposures to beneficial microbes, Commense is developing approaches to guide the priming, seeding, and maintaining of the microbiome in infants and children. Co-founded by PureTech Health (“PureTech,” LSE: PRTC) and working with the world’s leading microbiome scientists, physicians, and product developers, Commense is developing a novel category of products to address critical unmet needs in pediatric populations.
The Senior Scientist/Team Lead we are seeking will be a key member of Commense’s expanding leadership team, playing a critical role driving forward Commense’s immunology efforts. The Senior Scientist/Team Lead will spearhead the design and execution of studies to assess the ability of human commensal bacteria to elicit immune responses in in vitro cell-based assays, conventional mice, and germ free mouse models.
The ideal candidate must be passionate about translating bench findings to the clinic. The ideal candidate will have a mix of academic life science and biopharma industry experience. The candidate will anchor his/her priorities in line with business strategy, make decisions driven by data, influence and collaborate with all internal teams, and thrive in a startup-like environment.
- In partnership with strategy leaders of the team, design, plan, execute, and interpret in vitro, ex vivo, and in vivo studies using a variety of approaches and techniques
- Take observations and associations from human studies and develop assays to evaluate cellular pathways of host-microbe interactions
- Analysis and presentation of study data, provide scientific interpretations and recommendations in both team and company settings
- Lead and execute research projects independently, and ensure that projects support current company goals
- Foster a scientific culture of collaboration, innovation, rigor, and transparency
- Acknowledged authority within the corporation. Act as a leader of large-scale company initiatives. Viewed by peers as a leader and top contributor and by management as a key business partner. Have credibility with external subject matter experts.
- Train, supervise, and mentor junior staff, as needed
- Ph.D. in Immunology, Biology, Biochemistry, or related field, with post-doctoral training and significant contributions to the scientific field
- At least 5 years working in biotech or pharma; experience running science on industry time required
- Significant experience designing and working with mouse models of disease, managing a colony and experience in maintaining institutional protocols a plus.
- Expertise in ex vivo studies including flow cytometry, immunohistochemistry, immunology, and cell-based assays
- Expertise in cell and molecular biology, extensive experience in mammalian cell culture
- Experience in in vitro pharmacology and assay development is a plus
- Successful track record of building and leading teams in a technical lead role. Excellent leadership capabilities with demonstrated skill in building, guiding and motivating effective teams and fostering productive research collaborations
- Outstanding communication, interpersonal, and partnering skills
- Excellent cross-disciplinary skills in communicating scientific ideas to non-scientist stakeholders to foster collaboration and deliverable-based team work
- Experience working in the microbiome, autoimmunity, pediatric immunology, host-microbe, or inflammation fields highly desirable
- Startup experience is highly valued. Ability to adjust rapidly to changing scientific priorities and technologies
Location: Cambridge MA, USA.
Travel: This position requires travel up to 5% domestically and internationally